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The first working steam­ powered vehicle was designed and most likely built by Ferdinand Verbies, a Flemish member of a Jesuit mission in China around 1672. It was a 65 cm long scale­ model toy for the Chinese Emperor, that was unable to carry a driver or a passenger. It is not known if Verbiest's model was ever built. Nicolas- Joseph Cugnot is widely credited with building the first full­ scale, self ­propelled mechanical vehicle or automobile in about 1769; he also created a steam­ powered tricycle. He constructed two steam tractors for the French Army, one of which is preserved in the French National Conservatory of Arts and Crafts. His inventions were however handicapped by problems of water supply and maintaining steam pressure. In 1801, Richard Trevithick built and demonstrated his Puffing Devil road locomotive, believed by many to be the first demonstration of a steam ­powered road vehicle. It was unable to maintain sufficient steam pressure for long periods. Sentiment against steam ­powered road vehicles led to the Locomotive Acts of 1865. In 1807 Nicephore Niepce and his brother Claude probably created the world's first internal combustion engine which they called Pyreolophore.

The Pyreolophore was ?

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The antigen-antibody immunological reaction is used to be regarded as typical of immunological responses. Antibodies are proteins synthesized by specialized cells called plasma cells, which are formed by lymphocytes (cells from the lymph system) when an antigen, a substance foreign to an organism's body, comes in contact with lymphocytes. Two important manifestations of antigen-antibody immunity are lysis, the rapid physical rupture of antigenic cells and the liberation of their contents into the surrounding medium, and phagocytosis, a process in which antigenic particles are engulfed by and very often digested by macrophages and polymorphs. The process of lysis is executed by a complex and unstable blood constituent known as complement, which will not work unless it is activated by a specific antibody; the process of phagocytosis is greatly facilitated when the particles to be engulfed are coated by a specific antibody directed against them.

One of the two important manifestations of antigen-antibody immunity is lysis while the other is

In the following question, sentence given with blank to be filled in with an appropriate word(s). Four alternatives are suggested for the question. Choose the correct alternative out of the four and indicate it by selecting the appropriate option.

The king was _______ while he was addressing his subjects.

In the following question the 1st and the last part of the sentence/passage are numbered 1 and 6. The rest of the sentence/ passage is split into four parts and named P, Q, R and S. These four parts are not given in their proper order. Read the sentence/passage and find out which of the four combinations is correct.

1. I can't stand here and promise that your future path is going to be wonderful.
P. Whatever one feels like doing today is set up as moral.
Q. People don't even pretend to care about what is right.
R. Instead, it might be very difficult, because our time is different than some other eras in human history.
S. If you look around, you can see that, little by little, it is a path leading to our destruction.
6. I am afraid that this legacy of freedom is facing an uncertain future.

Who among the following has been named as the 2016 ITFWorld Champions by the International Tennis Federation?

In the following question, select the odd letter/ letters from the given alternatives

Who was the trusted General of the Mughal emperor Akbar?

Which of the following right has been removed from fundamental rights and converted to a simple legal right?