|A) Father||B) Brother|
|C) Uncle||D) Cannot be determined|
B is the son of C but C is not the mother of B means C is the father of B A is marned to C means A is the mother of B. F is brother of B means F is son of A and C. D is daughter of A means D is daughter of A and C
E is the brother of C who is the father of D. So. E is the uncle of D.